We are the Magnetic Resonance Core Facility of the Institute of Scientific Instruments - part of the Czech Bioimaging project.

The Preclinical Magnetic Resonance Unit in its current form has been established as a part of the Application Laboratories of Microtechnologies and Nanotechnologies of the Institute of Scientific Instruments (ALISI) in 2012 as a continuation of the institute’s tradition of nuclear magnetic resonance research and development reaching back to 1950s. Its principal mission is to support other academic institutions as well as commercial companies in their basic research and development of more efficient therapies or diagnostic markers, by means of magnetic resonance measurements of living small animals, plants, tissues or materials.

What do we do?

• Research into the mechanisms adversely affecting the accuracy, precision or speed of MR measurements
• Design of pulse sequences for specific applications
• Development of advanced data models and efficient analysis techniques

Our application areas:

• Perfusion measurement for quantitative pharmacokinetics
• Spectroscopy and spectroscopic imaging for metabolomics
• Advanced diffusometry
• Application-driven development of specialized MR imaging